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| Shah,Rehmat; Subhan,Fazal; Sultan,Syed Muhammad; Haq,Matiul; Ahmad,Hussain; Khan,Qasim Riaz; Ali,Gowhar; Ullah,Sami; Ullah,Ihsan. |
| Antipsychotic Drugs (APDs) are being widely prescribed to treat various disorders, including schizophrenia and bipolar disorder; however, abnormal glucose metabolism and weight gain have been reported with Atypical Anti-Psychotic drugs (AAPDs) that can lead to insulin-resistance and type 2 diabetes mellitus. The study was designed to assess various biochemical parameters including insulin and blood sugar before and after exposure to APDs in order to exclude the involvement of psychiatric disorders and certain other factors in metabolic dysregulations. Fifty seven APDs-naïve patients with first episode psychosis were divided into six groups who received olanzapine, quetiapine, risperidone, aripiprazole, haloperidol or combination of olanzapine with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Olanzapine; Quetiapine; Risperidone; Antipsychotics; Pancreas; Insulin. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100535 |
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| Silva,Deborah Galvão Coelho da; Kanazawa,Luiz Kae Sales; Vecchia,Débora Dalla. |
| Schizophrenia, in general, is characterized by severe and disabling mental alterations, characterized by the impairment of one’s mental, behavioral and social activities, developing certain clinical symptoms, relevant to the diagnosis. The drugs used for the reversion of the symptoms cause several adverse effects that affect the patient’s health and well-being, such as motor, endocrine and cardiovascular damages. For a long time, little was known about the origin and the treatment of schizophrenia, which has become a curiosity for science, originating countless researches and theories that are background for several treatments. It is known that alterations in dopaminergic pathways are related to the development of the symptoms of the disease, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Schizophrenia; Pharmacotherapy; Antipsychotics; Aripiprazole; Metabolic Syndrome. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100552 |
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